Neuromuscular versus quadriceps strengthening exercise in patients with medial knee osteoarthritis and varus malalignment: A randomized controlled trial

KL Bennell; M Kyriakides; B Metcalf; T Egerton; TV Wrigley; PW Hodges; MA Hunt; EM Roos; A Forbes; E Ageberg; RS Hinman

Journal article

Neuromuscular versus quadriceps strengthening exercise in patients with medial knee osteoarthritis and varus malalignment: A randomized controlled trial

KL Bennell, M Kyriakides, B Metcalf, T Egerton, TV Wrigley, PW Hodges, MA Hunt, EM Roos, A Forbes, E Ageberg, RS Hinman

Arthritis and Rheumatology | Published : 2014

DOI: 10.1002/art.38317

Abstract

Objective To compare the effects of neuromuscular exercise (NEXA) and quadriceps strengthening (QS) on the knee adduction moment (an indicator of mediolateral distribution of knee load), pain, and physical function in patients with medial knee joint osteoarthritis (OA) and varus malalignment. Methods One hundred patients with medial knee pain, mostly moderate-to-severe radiographic medial knee OA, and varus malalignment were randomly allocated to one of two 12-week exercise programs. Each program involved 14 individually supervised exercise sessions with a physiotherapist plus a home exercise component. Primary outcomes were peak external knee adduction moment (3-dimensional gait analysis), ..

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University of Melbourne Researchers

Kim Bennell Author

Ben Metcalf Author

Thorlene Egerton Author

Rana Hinman Author

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Grants

Funding Acknowledgements

Supported by the National Health and Medical Research Council (project grant 628644). Dr. Bennell's work was supported in part by the Australian Research Council (Future Fellowship FT0991413). Dr. Hodges' work was supported by the National Health and Medical Research Council (Fellowship 1002190).The University of Melbourne, Dr. Bennell, Mr. Wrigley, and Dr. Hinman receive royalties from ASICS Oceanic Pty., Ltd. for a modified shoe for managing symptoms and minimalizing structural deterioration in knee osteoarthritis. The University of Melbourne and Drs. Bennell and Hinman received royalties for the commercial use of an osteoarthritis DVD. Dr. Roos has received consulting fees, speaking fees, and/or honoraria from Ossur and the Finnish Orthopaedic Society (less than $10,000 each) and receives textbook royalties from Studentlitteratur and Munksgaard.